Second Generation FIT® is a five minute, at home test that is FDA cleared for use in physician offices and laboratories, as well as OTC cleared for use at home without a prescription. The data below is presented from the 2022 American College of Surgeons landmark meta-analysis comparing FIT to a leading mt-sdna test.


Second Generation FIT® is the go-to colon cancer screening test for hospitals, health fairs and non-profits who are screening large numbers of people.

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Among cancer deaths, colorectal cancer is the third-leading cause in both men and women. The American Cancer Society estimates colorectal cancer will kill 52,980 people in the U.S. this year. But it doesn’t have to be that way.  The Second Generation FIT test from Pinnacle BioLabs detects the biomarker for colorectal cancer, as well as diverticulitis, colitis, Crohn’s Disease, IBD, IBS, and polyps — at at microscopic levels. Elevated B++ globin, a protein in hemoglobin, (a component of human blood) is a primary indicator of lower GI disease. 

Fecal Immunochemical Test

FIT stands for fecal immunochemical test. The Second Generation FIT test is our most advanced colorectal cancer test, and is OTC approved and CLIA waived by the US FDA.  Second Generation FIT is easy and quick, and in five minutes or less allows you to assess your risk of colorectal cancer and other GI disease states.  Simply open the kit, collect a small sample of your stool with the provided collection tool and add three drops of solution to the cassette well.   Results are available within four to seven minutes. This next generation fecal immunochemical test is done entirely at home, removing the need to return fecal samples to a laboratory.

It’s important to remember that a positive result on a FIT test does not mean you have cancer. It means you should see your doctor to schedule a colonoscopy. While the hemoglobin biomarker is a symptom of cancer, it can be due to causes other than cancer, mentioned above.

Fecal Immunochemical tests (FIT tests) are considered the number one alternative to colonoscopy by the American College of Gastroenterology and the American Gastroenterological Association. In fact, the AGA gave the FIT test a grade of 1A in its most recent Colon Cancer Screening Guidelines, the same grade it gave to colonoscopy.

Getting a Colonoscopy

Colonoscopies are critically important tools that help save lives. The procedure itself is painless and easy, as patients are under anesthesia for it. However, the days leading up to it are neither, unfortunately.

You must begin avoiding certain foods several days before the procedure, then switch to a clear-liquid diet. After that, you must drink a substance that cleans out what’s left in your colon, and then no food or drink for hours before the procedure.

This is a challenge for hardy folks; for the frail and elderly, it can be near impossible. At one time, this segment of the population could be hospitalized in the days leading up to a colonoscopy, but insurance stopped paying for this years ago.

If you’re a relative of an ailing or elderly person, it can be hard to take time off work to help them prepare for a colonoscopy. If you are taking the test yourself, the days of preparation and the test itself will also interfere with going to work.

FIT Tests from Pinnacle Biolabs

If you or someone you know is thinking of getting a colonoscopy but isn’t sure they want to go through the hassle, get an at-home colon test instead.

While at-home colonoscopy tests are incredibly convenient, it’s important to get reliable one. Your health depends on it. Pinnacle Biolabs is known for having one of the best at-home colon cancer test kits available today. You can order yours on our site with no prescription or doctors visit.

Nothing is more important than your health. Take a proactive approach to colon cancer by ordering the FIT test today.  Second Generation FIT not only provides accurate results, it provides peace of mind.